LACTATE UPTAKE BY THE FETAL LIVER
نویسندگان
چکیده
منابع مشابه
Simultaneous measurements of lactate turnover rate and umbilical lactate uptake in the fetal lamb.
Lactic acid represents a major exogenous nutrient for the developing fetal lamb in utero. Our study was undertaken (a) to quantitate the net consumption of lactate by the fetus, (b) to quantitate the net lactate production and metabolism by the placenta, and (c) to compare the net fetal lactate consumption with fetal lactate use, measured simultaneously with radioactive tracers. 14 pregnant she...
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Multiple-indicator dilution experiments with labeled lactate were performed in the livers of anesthetized dogs. A mixture of (51)Cr-labeled erythrocytes, [(3)H]sucrose, and L-[1-(14)C]lactate or a mixture of (51)Cr-labeled erythrocytes, [(14)C]sucrose, and L-[2-(3)H]lactate was injected into the portal vein, and samples were obtained from the hepatic vein. Data were evaluated using a model comp...
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Lactale Uptake and Metabolism by Brain During Hyperlactatemia and Hypoglycemia • Entry into CSF and consumption by brain of blood-borne lactate (La) was quantified in pentobarbital-anesthetized, normocapnic dogs loaded and infused with NaLa and HLa to hold constant, in arterial blood, both the La concentration at about 8 mM (normal = 1 mM) and the pH at 7.4. In four dogs studied hourly over six...
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Mechanisms of hepatic lactate uptake were studied in the gulf toadfish, Opsanus beta by following the accumulation of [C]lactate by isolated hepatocytes in vitro. Uptake rates were linear for up to 5 s at external lactate concentrations of 1 and 20mmoll~'. 5-s uptake rates for several concentrations in the physiological range (i.e. 0-2-20mmoll") yielded a linear double reciprocal plot (l/v vs l...
متن کاملErythropoietin production by the fetal liver in an adult environment.
To gain insight into the mammalian liver to kidney erythropoietin (Ep) switch, we heterotopically transplanted livers from preswitch, switched, and postswitch fetal and newborn lambs into normal adult sheep. Recipients' serum Ep and circulating reticulocyte levels were serially determined until rejection of the graft and compared with identical samples from sham-operated control adult ewes. Tra...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1984
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198404001-00269